Jimmy Harper – A wholesome, innocent, high school teenager who runs into trouble after he is lured into the dangerous world of reefer.

Lecturer – a severe authority figure who warns the audience of the perils of Reefer Madness.

Mary Lane – Jimmy’s sweetheart, a naïve, virginal teenage girl.

Jack Stone – The handsome and ruthless proprietor of the Reefer Den, a 30’s gangster movie-type.

Mae – An attractive, yet slightly haggard dame in her mid-30s, the hostess of the Reefer Den.

Ralph Wiley – a denizen of the Reefer Den, formally a fraternity man, his college days ended long ago due to his reefer habit.

Sally – a sexy and seductive resident of the Reefer Den, she possesses the libidinous soul of Mae West combined with the rat-a-tat moxie of vintage Barbara Stanwyck.

Placard Girl – throughout the play she reinforces the warnings of the Lecturer by holding large signs that clearly state the moral of what we’ve just seen.

Other characters –

  • Mr. Poppy
  • Irish Priest
  • Old Man
  • Radio Announcer
  • Ticket-Taker
  • Policeman
  • FDR
  • Jesus
  • George Washington
  • Sally’s Baby
  • Switch-Puller
  • Uncle Sam
  • Lady Liberty
  • Five-and-Dime Kid
  • Police Officer

Ensemble – Mixed gender group to represent Reefer Zombies, Kids at the Five-and-Dime, Jungle Orgy dancers, Angels, and patriotic background chorus in the Star-Spangled finale.